Channel 122329-kv1_gp

General data

• ICG id: 467
• ModelDB id: 122329
• Reference: Deister CA, Chan CS, Surmeier DJ, Wilson CJ (2009): Calcium-activated SK channels influence voltage-gated ion channels to determine the precision of firing in globus pallidus neurons.

Metadata classes

• Animal Model: mouse, rat
• Brain Area: basal ganglia, globus pallidus (GP)
• Neuron Type: globus pallidus (GP) neuron
• Runtime Q: Q3
• Subtype: 1.2

Metadata generic

• Age: P15-25 (rat), P17-22 (mouse)
• Authors: J Held, C Deister
• Comments: Kv1.2 channel model using hh-type activation/inactivation, by j held mar 2003. Taken from mercer et al. (2007), model no. 105385, with the following modifications: parameters vhm, vhh, vcm and vch changed (lines 32-35), extra params kv1tmscale and kv1thscale multiplied with kinetics (lines 87, 90), but default at 1 so no change. Animal model is from experiments in paper, channel kinetics come from previous study of gp (mercer et al. 2007).
• Runtime: 7.965
• Temperature: Model has temperature dependence, original at 22 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp