Channel 119266-kaprox

General data

• ICG id: 403
• ModelDB id: 119266
• Reference: Markaki M, Orphanoudakis S, Poirazi P (2005): Modelling reduced excitability in aged CA1 neurons as a calcium-dependent process

Metadata classes

• Animal Model: rat
• Brain Area: hippocampus, CA1
• Neuron Region: unspecified
• Neuron Type: pyramidal cell
• Runtime Q: Q2
• Subtype: A

Metadata generic

• Age: adult
• Authors: M Migliore, Brannon, Y Poirazi, C Gold, M Markaki
• Comments: K-a channel from klee ficker and heinemann, modified by brannon and y poirazi to account for hoffman et al (1997) distal region kinetics, modified to work with cvode by c gold, updated by m markaki 2003. According to paper, this was taken from poirazi et al. (2003), model no. 20212, with various differences between the mod files. This is strictly modeling, with the model taken from a previous paper. Animal model is from ancestry, and is listed as adult because this is a model of an aged pyramidal cell.
• Runtime: 7.671
• Temperature: Model has temperature dependence.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp