Channel 184139-Kdr

General data

• ICG id: 3732
• ModelDB id: 184139
• Reference: Hyun JH, Eom K, Lee KH, Bae JY, Bae YC, Kim MH, Kim S, Ho WK, Lee SH (2015): Kv1.2 mediates heterosynaptic modulation of direct cortical synaptic inputs in CA3 pyramidal cells.

Metadata classes

• Animal Model: mouse, rat
• Brain Area: CA3, hippocampus
• Neuron Region: dendrites
• Neuron Type: pyramidal cell
• Subtype: delayed rectifier (dr)

Metadata generic

• Age: P13 to P24
• Authors: JH Hyun
• Comments: K-DR channel from Klee Ficker and Heinemann modified to account for Dax et al. LSH changed 1) gmn from 0.7 to 0.5 to make tau faster 2) vhalfn, 13 -> -3.8 (Kim Jonas, 2012).
• Temperature: Temperature dependent

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp