Channel 184139-Kaprox

General data

• ICG id: 3730
• ModelDB id: 184139
• Reference: Hyun JH, Eom K, Lee KH, Bae JY, Bae YC, Kim MH, Kim S, Ho WK, Lee SH (2015): Kv1.2 mediates heterosynaptic modulation of direct cortical synaptic inputs in CA3 pyramidal cells.

Metadata classes

• Animal Model: mouse, rat
• Brain Area: CA3, hippocampus
• Neuron Region: dendrites
• Neuron Type: pyramidal cell
• Subtype: A

Metadata generic

• Age: P13 to P24
• Authors: JH Hyun
• Comments: K-A channel from Klee Ficker and Heinemann modified to account for Dax A Current. The original model results in too big window current, which is robably contamination of D-type current. To reduce the window current component, LSH changed vhalfn, zeatan and zetal. To fit these parameters to Kim Jonas (2012), they should be -5, -65, -1.8, 3.7, respectively.
• Temperature: celsius = 24 (degC)

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp