Channel 149737-kfast

General data

• ICG id: 3196
• ModelDB id: 149737
• Reference: Wang K, Riera J, Enjieu-Kadji H, Kawashima R (2013): The role of extracellular conductivity profiles in compartmental models for neurons: particulars for layer 5 pyramidal cells.

Metadata classes

• Animal Model: rat
• Brain Area: layer 5, cortex
• Neuron Type: pyramidal cell
• Runtime Q: Q4 (slow)
• Subtype: fast

Metadata generic

• Age: juvenile (P14-16)
• Authors: M Migliore
• Comments: Kfast channel, from keren et al. (2005) (not on modeldb). Originally from korngreen and sakmann (2000), model no. 3289, with the following changes: gbar set to 0 (line 24), temperature dependence not used in kinetics (lines 79, 80). Modeling study, with no experimental results. Authors mention that channel parameters were meant to match those of a juvenile rat (pg. 1818), so this is interpreted as the animal model. Otherwise, this can be considered generic.
• Runtime: 8.312
• Temperature: Model has temperature dependence. Original kinetics were at 21 deg C, and q10 is set to 2.3.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp