Channel 151126-kdr

General data

• ICG id: 3117
• ModelDB id: 151126
• Reference: Bianchi D, De Michele P, Marchetti C, Tirozzi B, Cuomo S, Marie H, Migliore M (2014): Effects of increasing CREB-dependent transcription on the storage and recall processes in a hippocampal CA1 microcircuit.

Metadata classes

• Animal Model: rat
• Brain Area: hippocampus, CA1
• Neuron Type: pyramidal cell
• Runtime Q: Q3
• Subtype: delayed rectifier (dr)

Metadata generic

• Age: P19-24
• Authors: M Migliore
• Comments: K-dr channel from klee ficker and heinemann, modified to account for dax et al., by m migliore 1997. Taken from bianchi et al. 2012, model no. 143719, with the following changes: shift parameter sh added to kinetics, gmn parameter changed to 0.8 (line 20). Used in ca1 pyramidal neuron. Modeling study, animal model is from experiments in previous modeling study (bianchi et al. 2010).
• Runtime: 7.76
• Temperature: Model has temperature dependence.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp