Channel 151126-kaprox

General data

• ICG id: 3113
• ModelDB id: 151126
• Reference: Bianchi D, De Michele P, Marchetti C, Tirozzi B, Cuomo S, Marie H, Migliore M (2014): Effects of increasing CREB-dependent transcription on the storage and recall processes in a hippocampal CA1 microcircuit.

Metadata classes

• Animal Model: rat
• Brain Area: hippocampus, CA1
• Neuron Type: pyramidal cell
• Runtime Q: Q4 (slow)
• Subtype: A

Metadata generic

• Age: P19-24
• Authors: M Migliore, M Markaki, Brannon, Y Poirazi
• Comments: K-a channel from klee ficker and heinemann, modified by brannon & yiota poirazi. Used only in soma and proximal dendrites. Taken from bianchi et al. 2010, model no. 143719, with the following change: shift parameter sh added to kinetics. Used in ca1 pyramidal neuron. Modeling study, animal model is from experiments in previous modeling study (bianchi et al. 2010).
• Runtime: 8.287
• Temperature: Model has temperature dependence, default at 22 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp