Channel 115356-ka

General data

• ICG id: 264
• ModelDB id: 115356
• Reference: Royeck M, Horstmann MT, Remy S, Reitze M, Yaari Y, Beck H (2008): Role of axonal NaV1.6 sodium channels in action potential initiation of CA1 pyramidal neurons.

Metadata classes

• Animal Model: mouse
• Brain Area: hippocampus, CA1
• Neuron Region: soma, dendrites, axon, distal dendrites, apical dendrites, axon initial segment (AIS)
• Neuron Type: pyramidal cell
• Runtime Q: Q1 (fast)
• Subtype: A

Metadata generic

• Age: 17-21 days
• Authors: D Golomb, M Horstmann.
• Comments: Ka channel from golomb, yue, yaari (2006), model no. 66268 (in xpp), slow time-constant introduced, no model db ancestors. Experimental study along with modeling, with morphology from varona et al. (2000) and kinetics from golomb et al. (2006). The animal model info here is from the experiments in this paper.
• Runtime: 7.208
• Temperature: Model has no apparent temperature dependence.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp