Channel 97860-kv1_gp

General data

• ICG id: 2565
• ModelDB id: 97860
• Reference: Chan CS, Guzman JN, Ilijic E, Mercer JN, Rick C, Tkatch T, Meredith GE, Surmeier DJ (2007): 'Rejuvenation' protects neurons in mouse models of Parkinson's disease.

Metadata classes

• Animal Model: mouse
• Brain Area: basal ganglia, substantia nigra pars compacta (SNc)
• Neuron Region: single compartment
• Neuron Type: dopaminergic
• Runtime Q: Q4 (slow)
• Subtype: 1.2

Metadata generic

• Age: adult (<P28), juvenile (<P21)
• Authors: J Held
• Comments: Kv1.2 channel model using hh-type activation/inactivation, no apparent model db ancestors. Animal model comes from experiments in paper. Channel kinetics are mostly from unspecified sources.
• Runtime: 8.179
• Temperature: Model has temperature dependence, with original kinetics at 22 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp