Channel 9769-kdrca1

General data

• ICG id: 2549
• ModelDB id: 9769
• Reference: Poolos NP, Migliore M, Johnston D (2002): Pharmacological upregulation of h-channels reduces the excitability of pyramidal neuron dendrites.

Metadata classes

• Animal Model: Sprague-Dawley, rat
• Brain Area: hippocampus, CA1
• Neuron Region: soma, axon
• Neuron Type: pyramidal cell
• Runtime Q: Q3
• Subtype: delayed rectifier (dr)

Metadata generic

• Age: 6-10 weeks old
• Authors: M Migliore
• Comments: K-dr channel from klee ficker and heinemann, modified to account for dax et al., implemented by m. Migliore 1997. From migliore et al. (1999), model no. 2796, with no changes (identical mod file). This paper features experimental data as well as modeling. The animal model info below reflects the experimental data here, although this did not change the implementation of kdr, which remained the same. Both the ancestor and this current model feature rat ca1 pyramidal neuron.
• Runtime: 7.839
• Temperature: Model has temperature dependence.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp