Channel 114685-KDRf

General data

• ICG id: 243
• ModelDB id: 114685
• Reference: Johnson MD, McIntyre CC (2008): Quantifying the neural elements activated and inhibited by globus pallidus deep brain stimulation.

Metadata classes

• Animal Model: rat, monkey, macaque
• Brain Area: external globus pallidus (GPe), basal ganglia, internal globus pallidus (GPi), globus pallidus (GP), entopeduncular nucleus (EP) -- basal ganglia
• Neuron Region: soma, dendrites
• Runtime Q: Q1 (fast)
• Subtype: delayed rectifier (dr)

Metadata generic

• Authors: MD Johnson
• Comments: Potassium delayed rectifier kv3.1/3.2 membrane channel with fast deactivating components. Based on derived kinetics from baranauskas (1999) and hernandez (1999). No apparent model db ancestors. Modeling study that uses morphology and other data from monkey, and other physiology information from rat ep, the gp analogue.
• Runtime: 7.075
• Temperature: Kinetics modified to work for simulations at 36 deg C. No standard temperature dependence.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp