Channel 114685-AXNODE75

In other classes Na

General data

• ICG id: 240
• ModelDB id: 114685
• Reference: Johnson MD, McIntyre CC (2008): Quantifying the neural elements activated and inhibited by globus pallidus deep brain stimulation.

Metadata classes

• Animal Model: rat, monkey, macaque
• Brain Area: external globus pallidus (GPe), basal ganglia, internal globus pallidus (GPi), globus pallidus (GP), entopeduncular nucleus (EP) -- basal ganglia
• Neuron Region: soma, dendrites
• Runtime Q: Q4 (slow)
• Subtype: HH

Metadata generic

• Authors: Unknown
• Comments: Axonal node channels, based on axon model from mcintyre 2004. Fast na+, persistent na+, slow k+ and leakage currents responsible for nodal action potential. From miocinovic et al. (2006), model no. 151460, with no apparent changes to kinetics. Modeling study that uses morphology and other data from monkey, and other physiology information from rat ep, the gp analogue.
• Runtime: 5.17
• Temperature: Model has temperature dependence

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp