Channel 80769-Kv4

General data

• ICG id: 2366
• ModelDB id: 80769
• Reference: Akemann W, Knopfel T (2006): Interaction of Kv3 potassium channels and resurgent sodium current influences the rate of spontaneous firing of Purkinje neurons.

Metadata classes

• Animal Model: mouse
• Brain Area: cerebellum, Purkinje cell layer
• Neuron Region: unspecified
• Neuron Type: Purkinje cell
• Runtime Q: Q4 (slow)
• Subtype: 4

Metadata generic

• Age: P18-27
• Authors: W Akemann
• Comments: Voltage-gated low threshold potassium current from kv4 (primarily 4.3) subunits, h-h (1952) m^4*h kinetic scheme, data from sacco and tempia (2002). No model db ancestors. Animal model comes from results in this paper. Model comes from a previous study on cerebellar purkinje cells, with modification.
• Runtime: 8.238
• Temperature: Model has temperature dependence. Simulations and experiments done at 24 deg C. Ancestor paper was simulated at 22 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp