Channel 80769-Kv1

General data

• ICG id: 2365
• ModelDB id: 80769
• Reference: Akemann W, Knopfel T (2006): Interaction of Kv3 potassium channels and resurgent sodium current influences the rate of spontaneous firing of Purkinje neurons.

Metadata classes

• Animal Model: mouse
• Brain Area: cerebellum, Purkinje cell layer
• Neuron Region: unspecified
• Neuron Type: Purkinje cell
• Runtime Q: Q3
• Subtype: 1

Metadata generic

• Age: P18-27
• Authors: W Akemann
• Comments: Voltage-gated low threshold potassium current from kv1.1 subunits, h-h (1952) m^4 kinetic scheme, no inactivation. Kinetic data from zerr et al. (1998), and mckay et al. (2005). No model db ancestors. Animal model comes from results in this paper. Model comes from a previous study on cerebellar purkinje cells, with modification.
• Runtime: 7.98
• Temperature: Model has temperature dependence. Simulations and experiments done at 24 deg C. Ancestor paper was simulated at 22 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp