Channel 39949-kir2

General data

• ICG id: 1997
• ModelDB id: 39949
• Reference: Gruber AJ, Solla SA, Surmeier DJ, Houk JC (2003): Modulation of striatal single units by expected reward: a spiny neuron model displaying dopamine-induced bistability.

Metadata classes

• Brain Area: basal ganglia, striatum (basal ganglia)
• Neuron Region: single compartment
• Neuron Type: spiny cell
• Runtime Q: Q2
• Subtype: inward rectifier (IR, IR2, IRK)

Metadata generic

• Comments: Inward-rectifying k+ current (kir2 type). Parameters based on mermelstein et al (1998). Activation time constant may differ between the paper and mod file. No model db ancestors. Animal and neuron model is as specified in the paper. No animal model or experiments are mentioned, although most of the previous experimental data mentioned is from rats. Parameters for the ir-type k channel came from previous experiments on rat nucleus accumbens medium spiny neurons (mermelstein et al. 1998).
• Runtime: 7.553
• Temperature: No temperature dependence.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp