Channel 3289-kfast

General data

• ICG id: 1774
• ModelDB id: 3289
• Reference: Korngreen A, Sakmann B (2000): Voltage-gated K+ channels in layer 5 neocortical pyramidal neurones from young rats: subtypes and gradients.

Metadata classes

• Animal Model: rat
• Brain Area: somatosensory cortex, layer 5, cortex
• Neuron Type: pyramidal cell
• Runtime Q: Q4 (slow)
• Subtype: fast

Metadata generic

• Age: P13-15
• Authors: M Migliore
• Comments: Fast inactivating outward voltage-gated k channel in layer 5 neocortical pyramidal neurons. Implemented by migliore in 2001, for this paper. Kinetics described by a fourth-order hodgkin-huxley model for activation and first order for inactivation. No modeldb ancestors. Animal model is from paper (channel kinetics fit to expts), channel models appear to have been made independently.
• Runtime: 8.119
• Temperature: Model has temperature dependence, with q10 set to 2.3 and original kinetics at 22 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp