Channel 101629-km

General data

• ICG id: 12
• ModelDB id: 101629
• Reference: Hemond P, Epstein D, Boley A, Migliore M, Ascoli GA, Jaffe DB (2008): Distinct classes of pyramidal cells exhibit mutually exclusive firing patterns in hippocampal area CA3b.

Metadata classes

• Animal Model: Sprague-Dawley, rat
• Brain Area: CA3, hippocampus
• Neuron Region: soma
• Neuron Type: pyramidal cell
• Runtime Q: Q2
• Subtype: m

Metadata generic

• Age: 4-6 weeks old
• Authors: M Migliore
• Comments: Ca1 km channel from mala shah, by m migliore jun 2006. This is the same thing as kcnq. Paper cites migliore et al. (1995), model no. 3263, with various modifications. Due to comment in mod file, this might actually come from shah et al. (2008), model no. 112546. Experimental results (animal model info here) as well as modeling.
• Runtime: 7.625
• Temperature: Model has temperature dependence. Experiments done at 34 deg C, no mention of simulation temperature.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp