Channel 139653-SKv3_1

General data

• ICG id: 1095
• ModelDB id: 139653
• Reference: Hay E, Hill S, Schurmann F, Markram H, Segev I (2011): Models of neocortical layer 5b pyramidal cells capturing a wide range of dendritic and perisomatic active properties.

Metadata classes

• Animal Model: Wistar, rat
• Brain Area: layer 5, cortex
• Neuron Region: soma, dendrites
• Neuron Type: pyramidal cell
• Runtime Q: Q2
• Subtype: 3.1

Metadata generic

• Age: P36
• Authors: E Hay
• Comments: Kv3.1 channel, based on rettig et al. (1992) - characterization of a shaw-related potassium channel family in rat brain. No model db ancestors. Modeling study, that is constrained by experimental data (animal model here) (see le be et al. 2007). Channel kinetics come from various sources.
• Runtime: 7.488
• Temperature: No apparent temperature dependence. Simulations done at 34 deg C.

Current Response Traces

Activation

Inactivation

Deactivation

Action Potential

Ramp